Serum Homocysteine Levels in Patients with Non-alcoholic Fatty Liver Disease
نویسندگان
چکیده
Non-alcoholic fatty liver disease (NAFLD) which was characterized by the association of fatty liver and lobular hepatitis and chronically elevated plasma levels of alanine transaminase (ALT) in patients with negligible alcohol intake was first identified by Ludwig et al (1). The etiology of NAFLD is not known completely, but it is found in a variety of clinical settings, particularly in those patients with obesity, diabetes or hyperlipidemia (2-4). However, predisposing factor is not defined in some cases. In addition, the pathogenesis of NAFLD remains unclear. A central role for cytotoxic free fatty acids released from the accumulation of intrahepatic triglycerides is one mechanism in SERUM HOMOCYSTEINE LEVELS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
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